Dividuals. The Kruskal-Wallis test indicated TXA2/TP Agonist drug substantial variations for some components in between specimens considering sex and age. Nevertheless, the statistical evaluation has not a fantastic robustness because of low sample numbers, particularly thinking of the comparison in between female juveniles (n 2) and male juveniles (n six). Therefore, these benefits must be presented carefully.3.2. Geographical variability The heat maps to trace metals Mn (Figure three), As (Supplementary Fig. five), Cd (Supplementary Fig. six), Cr (Supplementary Fig. 7), CuJ.H. Pedrobom et al.Heliyon 7 (2021) eTable two. Concentrations of trace metals (mg kg-1 d.w.) in liver of Larus dominicanus.Sex As M F J (n six) A (n eight) J (n 2) A (n 14) Total (n 30) Cd M F J (n 6) A (n 8) J (n 2) A (n 14) Total (n 30) Cr M F J (n 6) A (n eight) J (n two) A (n 14) Total (n 30) Cu M F J (n 6) A (n eight) J (n 2) A (n 14) Total (n 30) Pb M F J (n 6) A (n eight) J (n 2) A (n 14) Total (n 30) Mn M F J (n 6) A (n 8) J (n two) A (n 14) Total (n 30) Mo M F J (n 6) A (n eight) J (n two) A (n 14) Total (n 30) Zn M F J (n 6) A (n 8) J (n two) A (n 14) Total (n 30) Ni M F J (n 6) A (n eight) J (n 2) A (n 14) Total (n 30) Ba M F J (n six) A (n eight) J (n 2) A (n 14) Total (n 30) V M F J (n six) A (n 8) J (n 2) A (n 14) Total (n 30) Hg M F J (n 6) A (n 8) J (n two) A (n 14) Total (n 30) Mean sd 2.six 2 two.2 2 5.9 1 2.six 3 two.7 three 0.1 0.1 0.four 0.2 0.2 0.1 0.five 0.three 0.four 0.3 LD 0.1 0.1 LD LD LD 13 3 14 2 9 0.3 15 4 14 three 0.06 0.03 0.14 0.15 0.06 0.03 1.20 4 0.6 three 10 3 12 2 13 1 11 3 11 3 1.8 0.four 2.0 0.four 1.eight 0.5 2.0 0.5 1.9 0.4 177 110 114 77 254 183 107 52 133 88 LD LD LD LD LD 0.1 0.1 LD LD LD LD 0.3 0.2 0.eight 1.6 0.2 0.3 0.2 0.1 0.four 0.eight three.6 two 2.six 2 4.8 0.1 2.9 2 3.1 2 six.1 0.eight six.two 0.four 0.five 0.01 4.6 0.1 0.1 LD 0.two LD LD LD 0.1 LD 384 36 303 71 two.eight 0.9 2.7 1.4 15 four 15 six 16 LD 0.five 0.02 26 9 18 9 LD LD 0.30 LD 1.two 0.1 0.8 0.1 12 0.2 Maximum 7 Minimum 0.M male, F female, J juvenile, A adult.J.H. Pedrobom et al.Heliyon 7 (2021) eFigure two. Principal Element Evaluation (PCA) of trace element concentrations in liver of Larus dominicanus. Female folks expressed in red spots (grouped by the red ellipse) and male people in blue spots (grouped by the blue ellipse).mechanism of detoxification of Hg, Sb, Ag, Cu or Pb, which indicated the greater concentrations of metals in juvenile people that had not yet undergone αLβ2 Inhibitor review moulting of feathers (Honda et al., 1985; Jakimska et al., 2011). Homeostatic interactions can control the accumulation of trace components, particularly of Cd. Thus, the presence of this metal within the liver of birds could indicate long-term exposure (Jakimska et al., 2011). In concordance with all the outcomes of reported by Corts and Luna-Jorquera e (2011) for livers of Larus dominicanus in Chile, benefits in the present work indicate larger concentrations of Cd in adult folks whencompared with juvenile people. This distinction might be related with all the chronic exposure to Cd. Metabolic processes in the translocation of primarily Zn from metallothionine result in greater accumulations of Cd in the liver, which indicates processes of bioaccumulation in adult folks (Jakimska et al., 2011a; 2011b). In this way, the results showed within the present study indicate the existence of an important mechanism of bioaccumulation of Cd associated to the age of Larus dominicanus. Metals like Cu, Zn and Mn are necessary for the metabolism or formation of pigments in bird feathers. Hence, these components can indicateFigure 3. Kernel maps of Mn concentration in liver.