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Product Name: ECH1 antibody
Applications: ICC/IF, IHC-P, WB
Predicted Target Size: 36 kDa (note) (2)
Positive Controls: A549 , HepG2 , mouse brain
Form Supplied: Liquid
Concentration: 0.71 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: enoyl CoA hydratase 1, peroxisomal
Background: This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators. [provided by RefSeq]
Synonyms: HPXEL antibody, ECH1 antibody, “delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial antibody”, “enoyl Coenzyme A hydratase 1, peroxisomal antibody”, peroxisomal enoyl-CoA hydratase 1 antibody, “delta3,5-delta2,4-dienoyl-CoA isomerase antibody”, dienoyl-CoA isomerase antibody, “enoyl CoA hydratase 1, peroxisomal antibody”
Cellular Localization: Mitochondrion , Peroxisome
CAS NO: 3544-24-9
Product: NVP-BKM120 (Hydrochloride)
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of human ECH1. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human, Mouse
Conjugation: Unconjugated
Storage Buffer: 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24711502?dopt=Abstract

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Markedly increased mitochondrial targeting possibly by growing the cystoplasmic pool of proteins offered for mitochondrial
Ucosa in mice. Interestingly, in our mouse study, DAPM suppressed tumorUcosa in mice. Interestingly, in
With the preclinical data presented here assistance the feasibility of aWith all the preclinical information
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Observed for the H257R mutant [27]. The central role of protonationObserved for the H257R mutant
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