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Product Name: ERK5 antibody [N2N3]
Applications: WB-Ag
Predicted Target Size: 88 kDa (note)
Positive Controls: Target recombinant protein
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: mitogen-activated protein kinase 7
Background: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. [provided by RefSeq]
Synonyms: BMK1 antibody, ERK4 antibody, ERK5 antibody, PRKM7 antibody, MAPK7 antibody, extracellular-signal-regulated kinase 5 antibody, MAPK 7 antibody, BMK1 kinase antibody, ERK-5 antibody, BMK-1 antibody, MAP kinase 7 antibody, extracellular signal-regulated kinase 5 antibody, mitogen-activated protein kinase 7 antibody, big MAP kinase 1 antibody
Cellular Localization: Cytoplasm , Nucleus
CAS NO: 572924-54-0
Ruxolitinib (phosphate)
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human ERK5. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity:
Conjugation: Unconjugated
Storage Buffer: 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27407148?dopt=Abstract

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But there are actually no intrachain backbone hydrogen bonds. Inside the solid state NMR derived
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Venging receptor on lymphatic endothelial cells. Especially, in the absence ofVenging receptor on lymphatic endothelial
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Roformate estersNIH-PA Author Manuscript NIH-PA Author ManuscriptCan Chem Trans. Author manuscript; offered in PMC 2014
Markedly increased mitochondrial targeting possibly by growing the cystoplasmic pool of proteins offered for mitochondrial
Ucosa in mice. Interestingly, in our mouse study, DAPM suppressed tumorUcosa in mice. Interestingly, in
With the preclinical data presented here assistance the feasibility of aWith all the preclinical information
Cancer in the United states of america, with an estimated 22,280 new instances detected and
E transport was SIK2 Inhibitor Biological Activity decreased in GDM pregnancies with regular fetal growth94,
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Observed for the H257R mutant [27]. The central role of protonationObserved for the H257R mutant
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