Product Name: FBXL11 antibody, Internal
Applications: IHC-P, WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration: Batch dependent mg/ml (Please refer to the vial label for the specific concentration)
Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Full Name: lysine (K)-specific demethylase 2A
Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 4 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-4 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least 6 highly degenerated leucine-rich repeats. Alternative splicing results in multiple transcript variants. [provided by RefSeq]
Synonyms: CXXCtype zinc finger protein 8, JmjC domaincontaining histone demethylation protein1A, Fbox protein FBL7, JmjC domain-containing histone demethylation protein 1A, F-, F, F-box and leucine-rich repeat protein 11, Fbox and leucinerich repeat protein 11, Fbox/LRRrepeat protein 11, Fbox and leucinerich repeat protein11, F-box/LRR-repeat protein 11, CXXCtype zinc finger protein8, Fbox/LRRrepeat protein11, KDM2A, F box/LRR repeat protein 11
Cellular Localization:
CAS NO: 958002-33-0
product targets : mAChR inhibitors
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: KLH conjugated synthetic peptide between 500-527 amino acids from the Central region of human JHDM1a/FBXL11.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: PBS, 0.09% sodium azide.
Storage Instruction: Keep as concentrated solution. For short-term storage, store at 4° C (up to 10 days). For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24909977?dopt=Abstract
