Product Name: FBXW11 antibody [N1C1]
Applications: WB
Predicted Target Size: 62 kDa (note) (3)
Positive Controls: 293T , A431 , H1299 , HeLaS3
Form Supplied: Liquid
Concentration: 0.19 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: F-box and WD repeat domain containing 11
Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons. [provided by RefSeq]
Synonyms: BTRC2 antibody, BTRCP2 antibody, FBW1B antibody, FBXW1B antibody, Fbw11 antibody, Hos antibody, KIAA0696 antibody, FBXW11 antibody, F-box and WD-40 domain protein 1B antibody, F-box and WD repeats protein beta-TrCP2 antibody, F-box protein Fbw1b antibody, F-box and WD-40 domain protein 11 antibody, beta-transducin repeat-containing protein 2 antibody, F-box/WD repeat-containing protein 1B antibody, homologous to Slimb protein antibody, F-box/WD repeat-containing protein 11 antibody, F-box and WD repeat domain containing 11 antibody
Cellular Localization: Cytoplasm
CAS NO: 1080645-95-9
product targets : STING inhibitors
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of human FBXW11. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: 1XPBS, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19828821?dopt=Abstract
