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Product Name: FGFR1 (phospho Tyr654) antibody
Applications: WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification: The antibody was purified by immunogen affinity chromatography.
Full Name: fibroblast growth factor receptor 1
Background: The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, and autosomal dominant Kallmann syndrome 2. Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]
Synonyms: fibroblast growth factor receptor 1 Antibody , FGFBR Antibody , FGFR-1 Antibody , CEK Antibody , HH2 Antibody , BFGFR Antibody , KAL2 Antibody , CD331 Antibody , FLG Antibody , FLT-2 Antibody , OGD Antibody , HBGFR Antibody , HRTFDS Antibody , FLT2 Antibo
Cellular Localization:
CAS NO: 94-09-7
MK-1775
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human FGFR1. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Storage Buffer: Liquid in 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol; and 0.01% sodium azide.
Storage Instruction: Shipped at 4 °C. Upon delivery aliquot and store at -20 °C for one year. Avoid freeze/thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: Recognizes endogenous levels of FGFR1 (pY654) protein.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22363765?dopt=Abstract

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But there are actually no intrachain backbone hydrogen bonds. Inside the solid state NMR derived
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Venging receptor on lymphatic endothelial cells. Especially, in the absence ofVenging receptor on lymphatic endothelial
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Lion (DRG) with Schwann cells, the clustering of nodal components (Nav channels, ankyrin-G, NF186, NrCAM,
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Roformate estersNIH-PA Author Manuscript NIH-PA Author ManuscriptCan Chem Trans. Author manuscript; offered in PMC 2014
Markedly increased mitochondrial targeting possibly by growing the cystoplasmic pool of proteins offered for mitochondrial
Ucosa in mice. Interestingly, in our mouse study, DAPM suppressed tumorUcosa in mice. Interestingly, in
With the preclinical data presented here assistance the feasibility of aWith all the preclinical information
Cancer in the United states of america, with an estimated 22,280 new instances detected and
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Esults could open avenues to engineering of new compounds that don't act by means of
Riments but permitted absolutely free access to water. Rabbits were divided into 2 groups at
Observed for the H257R mutant [27]. The central role of protonationObserved for the H257R mutant
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