Product Name: FTO antibody [5-2H10]
Applications: ICC/IF, WB
Predicted Target Size: 58 (note)
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification: Protein G purified
Full Name: fat mass and obesity associated
Background: Dioxygenase that repairs alkylated DNA and RNA by oxidative demethylation. Has highest activity towards single-stranded RNA containing 3-methyluracil, followed by single-stranded DNA containing 3-methylthymine. Has low demethylase activity towards single-stranded DNA containing 1-methyladenine or 3-methylcytosine. Has no activity towards 1-methylguanine. Has no detectable activity towards double-stranded DNA. Requires molecular oxygen, alpha-ketoglutarate and iron. Contributes to the regulation of the global metabolic rate, energy expenditure and energy homeostasis. Contributes to the regulation of body size and body fat accumulation.
Synonyms: FTO, KIAA1752, MGC5149
Cellular Localization:
CAS NO: 890190-22-4
Brand: MedChemExpress :Home
Host: Mouse
Clonality: Monoclonal
Isotype: IgG
Immunogen: Synthetic peptide corresponding to amino acid residues from the N-terminal region conjugated to KLH
Antigen Species: Human
Species Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Storage Buffer: 100 µl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.
Storage Instruction: For long-term storage, aliquot and store at -20 C. Avoid repeated freeze/thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22275233?dopt=Abstract
