Product Name: Fas Ligand antibody [Alf1.2]
Applications: ELISA, FACS, IP
Predicted Target Size:
Positive Controls: KFL 9
Form Supplied: Liquid
Concentration: ~1 mg/ml
Purification: Purified immunoglobulin
Full Name: Fas ligand
Background: This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described. [provided by RefSeq, Nov 2014]
Synonyms: CD95L Antibody , TNFSF6 Antibody , FASLG Antibody , ALPS1B Antibody , APT1LG1 Antibody , Fas ligand Antibody , APTL Antibody , CD178 Antibody , FASL Antibody
Cellular Localization:
CAS NO: 1872382-47-2
product targets : Glucagon Receptor inhibitors
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: recombinant soluble active extracellular domain of human Fas ligand.[6][4]
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: PBS pH 7.4, 1% BSA, 15mM Sodium Azide
Storage Instruction: Keep as concentrated solution. For short-term storage, store at 4° C (up to 10 days). For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25130653?dopt=Abstract
