Product Name: Flotillin 1 antibody [EP446Y]
Applications: WB
Predicted Target Size: 48 (note)
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification: Tissue culture supernatant
Full Name: flotillin 1
Background: Flotillin-1, also known as Reggie-2, belongs to a larger family of proteins that share an evolutionarily conserved stomatin/prohibitin/flotillin/HflK/C (SPFH) domain . Flotillin-1 is a lipid raft-associated protein that has been implicated in various cellular processes. Flotillin was first found in cells that lack morphologically definable caveolae, as well as in non-caveolar membranes and was subsequently identified in low density detergent-insoluble complexes of endothelial cells, where they were termed flotillins . As well as its postulated role in neuronal regeneration, flotilllin-1 has been implicated in insulin signaling to trigger glucose transporter redistribution in adipocytes Flotillin also associates with phagosomes in macrophages .
Synonyms: Flotillin1, Flotillin 1
Cellular Localization:
CAS NO: 923978-27-2
CUDC-907
Host: Rabbit
Clonality: Monoclonal
Isotype: IgG
Immunogen: A synthetic peptide corresponding to residues in human Flotillin-1 was used as immunogen.
Antigen Species: Human
Species Reactivity: Human, Mouse
Conjugation: Unconjugated
Storage Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage Instruction: Store at -20 °C. Stable for 12 months from date of receipt.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,488.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22935707?dopt=Abstract
