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Product Name: Fructose 6 Phosphate Kinase antibody [N1N2-2], N-term
Applications: WB
Predicted Target Size: 85 kDa (note) (4)
Positive Controls: 293T , mouse brain , rat brain
Form Supplied: Liquid
Concentration: 0.92 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: phosphofructokinase, muscle
Background: The PFKM gene encodes the muscle isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. Mammalian PFK is a tetramer made up of various combinations of 3 subunits: muscle (PFKM), liver (PFKL; MIM 171860), and platelet (PFKP; MIM 171840), the genes for which are located on chromosomes 12q13, 21q22, and 10p, respectively. The composition of the tetramers differs according to the tissue type. Muscle and liver PFK are a homotetramers of 4M and 4L subunits, respectively. Erythrocytes contain both L and M subunits, which randomly tetramerize to form M4, L4, and M3L, M2L2, and ML3 hybrid forms of the holoenzyme (Vora et al., 1980 [PubMed 6444721]; Raben and Sherman, 1995 [PubMed 7550225]).[supplied by OMIM]
Synonyms: GSD7 antibody, MGC8699 antibody, PFK-1 antibody, PFK1 antibody, PFKA antibody, PFKX antibody, PFKM antibody, phosphohexokinase antibody, phosphofructo-1-kinase isozyme A antibody, phosphofructokinase 1 antibody, phosphofructokinase-M antibody, “6-phosphofructokinase, muscle type antibody”, 6-phosphofructo-1-kinase antibody, “phosphofructokinase, polypeptide X antibody”, PFK-A antibody, “phosphofructokinase, muscle antibody”
Cellular Localization:
CAS NO: 200132-83-8
SCH900776
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human Fructose 6 Phosphate Kinase. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Storage Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25062348?dopt=Abstract

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Venging receptor on lymphatic endothelial cells. Especially, in the absence ofVenging receptor on lymphatic endothelial
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Roformate estersNIH-PA Author Manuscript NIH-PA Author ManuscriptCan Chem Trans. Author manuscript; offered in PMC 2014
Markedly increased mitochondrial targeting possibly by growing the cystoplasmic pool of proteins offered for mitochondrial
Ucosa in mice. Interestingly, in our mouse study, DAPM suppressed tumorUcosa in mice. Interestingly, in
With the preclinical data presented here assistance the feasibility of aWith all the preclinical information
Cancer in the United states of america, with an estimated 22,280 new instances detected and
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Observed for the H257R mutant [27]. The central role of protonationObserved for the H257R mutant
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