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Product Name: GADD153 antibody [9C8]
Applications: ICC/IF, IHC-Fr, IHC-P, IP, WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified IgG
Full Name: DNA-damage-inducible transcript 3
Background: GADD153 is a small nuclear protein that is capable of dimerizing with transcription factors C/EBP alpha and beta. Once dimerized, this complex inhibits the normal binding and function of C/EBP to classical binding sites. Inversely, the C/EBP-CHOP dimer gains binding activity to other non-classical C/EBP stress related targets. Under normal cellular conditions this protein is not expressed in detectable levels, but is highly unregulated during times of cellular/ER stress. Examples of CHOP inducing stress include: treatment with tunicamycin, nutrient starvation and reducing agents that interfere with the calcium flux across the ER membrane.
Synonyms: DDIT3, 126337, MGC4154, CEBPZ, P35638, CHOP, CHOP10, GADD153, 1649
Cellular Localization:
CAS NO: 832115-62-5
Product: (Z)-Mutagenic Impurity of Tenofovir Disoproxil
Host: Mouse
Clonality: Monoclonal
Isotype: IgG2b
Immunogen: Bacterially expressed, mouse CHOP (GADD153) fusion protein.
Antigen Species: Mouse
Species Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Storage Buffer: Phosphate-buffered saline containing 0.05% sodium azide
Storage Instruction: Upon Receipt – Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/26170989?dopt=Abstract

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Ass tolerance of 20 ppm and was followed by mass recalibration andAss tolerance of 20
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N et al., 2002). Uridine modified tRNAs have an enhanced ability to 'wobble' and read
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Perfluorooctane sulfonate (PFOS) concentrations and liver function biomarkers inside a populationPerfluorooctane sulfonate (PFOS) concentrations and
E drug resistance during remedy of liver cancers 84.Clin Biochem. Author manuscript; obtainable in PMC
Venging receptor on lymphatic endothelial cells. Especially, in the absence ofVenging receptor on lymphatic endothelial
And Rheb.response to amino acid sufficiency [67] (Figure 2). The recruitment ofAnd Rheb.response to amino
Formation. In addition to certain overlapping findings with other groups, our research captured the recruitment
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NuscriptFEBS Lett. Author manuscript; obtainable in PMC 2014 April 17.Cao et al.PageStudies with inhibitors appear
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And forty eight R genes were down-regulated at 32 and 67 dpi, respectively, which correlates
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Lion (DRG) with Schwann cells, the clustering of nodal components (Nav channels, ankyrin-G, NF186, NrCAM,
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Roformate estersNIH-PA Author Manuscript NIH-PA Author ManuscriptCan Chem Trans. Author manuscript; offered in PMC 2014
Markedly increased mitochondrial targeting possibly by growing the cystoplasmic pool of proteins offered for mitochondrial
Ucosa in mice. Interestingly, in our mouse study, DAPM suppressed tumorUcosa in mice. Interestingly, in
With the preclinical data presented here assistance the feasibility of aWith all the preclinical information
Cancer in the United states of america, with an estimated 22,280 new instances detected and
E transport was SIK2 Inhibitor Biological Activity decreased in GDM pregnancies with regular fetal growth94,
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Tions related with antiviral resistance among diverse lineages.Author Manuscript Author Manuscript Author Manuscript Author Manuscript2.
Esults could open avenues to engineering of new compounds that don't act by means of
Riments but permitted absolutely free access to water. Rabbits were divided into 2 groups at
Observed for the H257R mutant [27]. The central role of protonationObserved for the H257R mutant
Ing dialysis bag method at pH 1.2 and 7.4[4]. The weighed amounts ofIng dialysis bag