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Product Name: GCC2 antibody, Internal
Applications: IHC-P
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Full Name: GRIP and coiled-coil domain containing 2
Background: Golgin which probably tethers transport vesicles to the trans-Golgi network (TGN) and regulates vesicular transport between the endosomes and the Golgi. As a RAB9A effector it is involved in recycling of the mannose 6-phosphate receptor from the late endosomes to the TGN. May also play a role in transport between the recycling endosomes and the Golgi. Required for maintenance of the Golgi structure, it is involved in the biogenesis of noncentrosomal, Golgi-associated microtubules through recruitment of CLASP1 and CLASP2.
Synonyms: KIAA0336, GRIP and coiledcoil domain containing2, GCC185, GRIP and coiledcoil domain containing 2, CLL-associated antigen KW-11, CLLassociated antigen KW, GCC2, GRIP and coiledcoil domaincontaining2, CTCL tumor antigen se1-1, CLLassociated antigen KW11, GRIP coiledcoil protein GCC185, (Ranbinding protein 2like 4), GRIP and coiledcoil domaincontaining 2, GRIP coiledcoil protein GCC185, (Ranbinding protein2like4), CTCL tumor antigen se11, RANBP2L4, REN53, CLL associated antigen KW 11
Cellular Localization:
CAS NO: 456-59-7
Product: CC122
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Immunogen: C-QKLTNKNNKIED
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Storage Instruction: Aliquot and store at -20°C. Minimize freezing and thawing.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody is specific for GCC2.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27466374?dopt=Abstract

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