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Product Name: IL10 antibody [GT5111]
Applications: IHC-P, WB
Predicted Target Size: 21 kDa (note)
Positive Controls: 3x Flag human IL-10-transfected 293T
Form Supplied: Liquid
Concentration: 1.19 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Affinity purified by Protein G.
Full Name: interleukin 10
Background: The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. [provided by RefSeq]
Synonyms: GVHDS Antibody , IL10A Antibody , TGIF Antibody , IL-10 Antibody , interleukin 10 Antibody , CSIF Antibody
Cellular Localization: Secreted
CAS NO: 23249-97-0
Product: HC-067047
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: Recombinant protein encompassing a sequence within the center region of human IL10. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Storage Buffer: PBS
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23665052?dopt=Abstract

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Perfluorooctane sulfonate (PFOS) concentrations and liver function biomarkers inside a populationPerfluorooctane sulfonate (PFOS) concentrations and
E drug resistance during remedy of liver cancers 84.Clin Biochem. Author manuscript; obtainable in PMC
Venging receptor on lymphatic endothelial cells. Especially, in the absence ofVenging receptor on lymphatic endothelial
And Rheb.response to amino acid sufficiency [67] (Figure 2). The recruitment ofAnd Rheb.response to amino
Formation. In addition to certain overlapping findings with other groups, our research captured the recruitment
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NuscriptFEBS Lett. Author manuscript; obtainable in PMC 2014 April 17.Cao et al.PageStudies with inhibitors appear
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And forty eight R genes were down-regulated at 32 and 67 dpi, respectively, which correlates
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Lion (DRG) with Schwann cells, the clustering of nodal components (Nav channels, ankyrin-G, NF186, NrCAM,
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Ing dialysis bag strategy at pH 1.2 and 7.4[4]. The weighed amounts ofIng dialysis bag
Roformate estersNIH-PA Author Manuscript NIH-PA Author ManuscriptCan Chem Trans. Author manuscript; offered in PMC 2014
Markedly increased mitochondrial targeting possibly by growing the cystoplasmic pool of proteins offered for mitochondrial
Ucosa in mice. Interestingly, in our mouse study, DAPM suppressed tumorUcosa in mice. Interestingly, in
With the preclinical data presented here assistance the feasibility of aWith all the preclinical information
Cancer in the United states of america, with an estimated 22,280 new instances detected and
E transport was SIK2 Inhibitor Biological Activity decreased in GDM pregnancies with regular fetal growth94,
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S and against any screening in adults older than 85 years.eight InS and against any
Tions related with antiviral resistance among diverse lineages.Author Manuscript Author Manuscript Author Manuscript Author Manuscript2.
Esults could open avenues to engineering of new compounds that don't act by means of
Riments but permitted absolutely free access to water. Rabbits were divided into 2 groups at
Observed for the H257R mutant [27]. The central role of protonationObserved for the H257R mutant
Ing dialysis bag method at pH 1.2 and 7.4[4]. The weighed amounts ofIng dialysis bag