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Product Name: IL2 Receptor alpha antibody [MEM-140] (Biotin)
Applications: FACS
Predicted Target Size:
Positive Controls:
Form Supplied:
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification:
Full Name: interleukin 2 receptor, alpha
Background: The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.[provided by RefSeq]
Synonyms: CD25, P01589, TCGFR, IL2RA, IL2R, 3559, 147730, IDDM10
Cellular Localization:
CAS NO: 152658-17-8
Product: Seco Rapamycin (sodium salt)
Host: Mouse
Clonality: Monoclonal
Isotype: IgM
Immunogen: PHA-activated peripheral blood leucocytes.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Biotin
Storage Buffer: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
Storage Instruction: Keep as concentrated solution. Store at 4ºC short term. For extended storage aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: CD25 antigen (Interleukin-2 receptor alpha chain).
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/18322086?dopt=Abstract

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