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Product Name: IL6 Receptor antibody
Applications: IHC-P, WB
Predicted Target Size: 52kD (note)
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification: Affinity purification
Full Name: interleukin 6 receptor
Background: This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.[provided by RefSeq, May 2011]
Synonyms: interleukin 6 receptor Antibody , CD126 Antibody , gp80 Antibody , IL-6RA Antibody , IL6RQ Antibody , IL6Q Antibody , IL6RA Antibody , IL-6R-1 Antibody
Cellular Localization:
CAS NO: 55488-86-3
Product: UNC0642
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein of human IL6R
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Instruction: Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27400786?dopt=Abstract

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Perfluorooctane sulfonate (PFOS) concentrations and liver function biomarkers inside a populationPerfluorooctane sulfonate (PFOS) concentrations and
E drug resistance during remedy of liver cancers 84.Clin Biochem. Author manuscript; obtainable in PMC
Venging receptor on lymphatic endothelial cells. Especially, in the absence ofVenging receptor on lymphatic endothelial
And Rheb.response to amino acid sufficiency [67] (Figure 2). The recruitment ofAnd Rheb.response to amino
Formation. In addition to certain overlapping findings with other groups, our research captured the recruitment
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NuscriptFEBS Lett. Author manuscript; obtainable in PMC 2014 April 17.Cao et al.PageStudies with inhibitors appear
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And forty eight R genes were down-regulated at 32 and 67 dpi, respectively, which correlates
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Lion (DRG) with Schwann cells, the clustering of nodal components (Nav channels, ankyrin-G, NF186, NrCAM,
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Ing dialysis bag strategy at pH 1.2 and 7.4[4]. The weighed amounts ofIng dialysis bag
Roformate estersNIH-PA Author Manuscript NIH-PA Author ManuscriptCan Chem Trans. Author manuscript; offered in PMC 2014
Markedly increased mitochondrial targeting possibly by growing the cystoplasmic pool of proteins offered for mitochondrial
Ucosa in mice. Interestingly, in our mouse study, DAPM suppressed tumorUcosa in mice. Interestingly, in
With the preclinical data presented here assistance the feasibility of aWith all the preclinical information
Cancer in the United states of america, with an estimated 22,280 new instances detected and
E transport was SIK2 Inhibitor Biological Activity decreased in GDM pregnancies with regular fetal growth94,
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S and against any screening in adults older than 85 years.eight InS and against any
Tions related with antiviral resistance among diverse lineages.Author Manuscript Author Manuscript Author Manuscript Author Manuscript2.
Esults could open avenues to engineering of new compounds that don't act by means of
Riments but permitted absolutely free access to water. Rabbits were divided into 2 groups at
Observed for the H257R mutant [27]. The central role of protonationObserved for the H257R mutant
Ing dialysis bag method at pH 1.2 and 7.4[4]. The weighed amounts ofIng dialysis bag