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Product Name: IRE1 beta antibody
Applications: ELISA, ICC/IF, IHC-P
Predicted Target Size: 102 kDa (note)
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Full Name: endoplasmic reticulum to nucleus signaling 2
Background: Induces translational repression through 28S ribosomal RNA cleavage in response to ER stress. Pro-apoptotic. Appears to play no role in the unfolded-protein response, unlike closely related proteins.
Synonyms: hIRE2p, IRE1b, ERN2, Inositolrequiring protein2, Endoplasmic reticulum-to-nucleus signaling 2, Inositolrequiring protein 2, Ire1beta, Endoplasmic reticulumtonucleus signaling 2, Inositol-requiring protein 2, Endoplasmic reticulumtonucleus signaling2, Ire1-beta, Ire1 beta, Inositol requiring protein 2
Cellular Localization:
CAS NO: 1472624-85-3
Product: Calycosin
Host: Rabbit
Clonality: Polyclonal
Isotype:
Immunogen: The antiserum was produced against synthesized peptide derived from human ERN2.
Antigen Species: Human
Species Reactivity: Human, Mouse
Conjugation: Unconjugated
Storage Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Instruction: Store at -20 degrees Celcius. Product is stable for at least 1 year.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: ERN2 Antibody detects endogenous levels of total ERN2 protein.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24627478?dopt=Abstract

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