Product Name: IRF8 antibody, Internal
Applications: FACS, WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration: Batch dependent mg/ml (Please refer to the vial label for the specific concentration)
Purification: Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Full Name: interferon regulatory factor 8
Background: Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection. [provided by RefSeq]
Synonyms: Interferon consensus sequencebinding protein, IRF8, IRF-8, Interferon consensus sequence-binding protein, ICSBP, Interferon regulatory factor8, Interferon regulatory factor 8, ICSBP1, IRF 8
Cellular Localization:
CAS NO: 223645-67-8
Product: N-Acetyl-DL-phenylalanine
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: KLH conjugated synthetic peptide between 241-269 amino acids from the Central region of human IRF8.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: PBS, 0.09% sodium azide.
Storage Instruction: Keep as concentrated solution. For short-term storage, store at 4° C (up to 10 days). For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23447531?dopt=Abstract
