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Product Name: ITK antibody [2F12]
Applications: IP, WB
Predicted Target Size:
Positive Controls: Jurkat cells
Form Supplied: Liquid
Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Protein G purified
Full Name: IL2-inducible T-cell kinase
Background: ITK is a T cell signaling protein. The Tec family of non receptor tyrosine kinases is composed of six proteins designated Tec, ITK (also known as Emt or Tsk), Btk (previously known as Atk, BPK or Emb), Bmx, Txk (also known as Rlk) and Dsrc28C. All members of the family contain SH3 and SH2 domains and, with the exception of Txk and Dsrc28C, also contain pleckstrin homology (PH) and Tec homology (TH) domains in their amino termini. Tik associates with CD28 and becomes activated subsequent to CD28 ligation.
Synonyms: Emt, Tcsk, Tsk
Cellular Localization: Plasma membrane
CAS NO: 290297-26-6
Product: Modaline (sulfate)
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: Recombinant full length protein (Mouse).
Antigen Species: Mouse
Species Reactivity: Human, Mouse
Conjugation: Unconjugated
Storage Buffer: 10mM PBS, pH7.4, 0.2%BSA, 0.09% sodium azide
Storage Instruction: Keep as concentrated solution, aliquot and store at 4°C. Do not freeze.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21673110?dopt=Abstract

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Ion. Hypoxia is usually a well-known situation that induces epithelial-tomesenchymal transition (EMTIon. Hypoxia is usually
N et al., 2002). Uridine modified tRNAs have an enhanced ability to 'wobble' and read
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Nflammation and protects against cartilage and bone destruction. Remedy with exogenous IFN- also resulted within
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Act as a stabilizer in the membrane bilayer. Even so, additional studies are required to
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At 65 , and their fluorescent photos had been superimposed making use of Microarray
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Perfluorooctane sulfonate (PFOS) concentrations and liver function biomarkers inside a populationPerfluorooctane sulfonate (PFOS) concentrations and
E drug resistance during remedy of liver cancers 84.Clin Biochem. Author manuscript; obtainable in PMC
Venging receptor on lymphatic endothelial cells. Especially, in the absence ofVenging receptor on lymphatic endothelial
And Rheb.response to amino acid sufficiency [67] (Figure 2). The recruitment ofAnd Rheb.response to amino
Formation. In addition to certain overlapping findings with other groups, our research captured the recruitment
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S linked together with the pathogenesis of inflammatory processes [38-40]. Indeed, LPS induced NF-B activation
False negatives, due to the fact an interaction may possibly nevertheless persist upon mutating a
NuscriptFEBS Lett. Author manuscript; obtainable in PMC 2014 April 17.Cao et al.PageStudies with inhibitors appear
S, will not be accompanied by the loss of structural compactness ofS, is just not
Formed 14 days ( day) following the commence of radiotherapy (20 Gy). DW-MRI 2 andFormed
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And forty eight R genes were down-regulated at 32 and 67 dpi, respectively, which correlates
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How modification with the sourdough microbiota in comparison with profiles, which were discovered following collecting
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Lion (DRG) with Schwann cells, the clustering of nodal components (Nav channels, ankyrin-G, NF186, NrCAM,
Was unstable, and could automatically undergo 3,7-rearrangement reaction without having the helpWas unstable, and could
Ing dialysis bag strategy at pH 1.2 and 7.4[4]. The weighed amounts ofIng dialysis bag
Roformate estersNIH-PA Author Manuscript NIH-PA Author ManuscriptCan Chem Trans. Author manuscript; offered in PMC 2014
Markedly increased mitochondrial targeting possibly by growing the cystoplasmic pool of proteins offered for mitochondrial
Ucosa in mice. Interestingly, in our mouse study, DAPM suppressed tumorUcosa in mice. Interestingly, in
With the preclinical data presented here assistance the feasibility of aWith all the preclinical information
Cancer in the United states of america, with an estimated 22,280 new instances detected and
E transport was SIK2 Inhibitor Biological Activity decreased in GDM pregnancies with regular fetal growth94,
S no distinct labeling of balloon cells in the white matter with these markers.903 Oligodendroglia
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S and against any screening in adults older than 85 years.eight InS and against any
Tions related with antiviral resistance among diverse lineages.Author Manuscript Author Manuscript Author Manuscript Author Manuscript2.
Esults could open avenues to engineering of new compounds that don't act by means of
Riments but permitted absolutely free access to water. Rabbits were divided into 2 groups at
Observed for the H257R mutant [27]. The central role of protonationObserved for the H257R mutant
Ing dialysis bag method at pH 1.2 and 7.4[4]. The weighed amounts ofIng dialysis bag