Product Name: Influenza A virus M1 (matrix protein) antibody
Applications: ICC/IF, WB
Predicted Target Size: 28 kDa (note)
Positive Controls: Influenza virus (A/WSN/1933(H1N1))-infected DF-1 cell lysates, *influenza virus (A/WSN/33) infected MDCK
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: Influenza A Virus Matrix Protein 1 (M1)
Background: Influenza A virus matrix 1, M1, is a critical protein required for assembly and budding. Hemagglutinin associates with M1 via its cytoplasmic tail and transmembrane domain. The M2 and nucleoprotein proteins are critical in the replication cycle of influenza viruses. The M2 channel protein is an essential component of the viral envelope because of its ability to form a highly selective, pH-regulated, proton-conducting channel. The M2 channel allows protons to enter the interior of the virus and acidification weakens the interaction of the M1 protein with the ribonuclear core.
Synonyms:
Cellular Localization:
CAS NO: 844-26-8
Product: JNJ-7777120
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant fragment corresponding to C-terminal region of Influenza A virus M1 (A/Puerto Rico/8/1934(H1N1)). The exact sequence is proprietary.
Antigen Species: Influenza A virus ( H1N1)
Species Reactivity: Human, Influenza A virus
Conjugation: Unconjugated
Storage Buffer: 1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24440272?dopt=Abstract
