Product Name: LDB3 antibody
Applications: IHC-P, WB
Predicted Target Size: 77 kDa (note) (3)
Positive Controls: NT2D1 , RD , mouse muscle , rat muscle
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: LIM domain binding 3
Background: This gene encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified; all isoforms have N-terminal PDZ domains while only longer isoforms (1 and 2) have C-terminal LIM domains. [provided by RefSeq]
Synonyms: CMD1C antibody, CYPHER antibody, FLJ35865 antibody, KIAA01613 antibody, KIAA0613 antibody, LDB3Z1 antibody, LDB3Z4 antibody, LVNC3 antibody, ORACLE antibody, PDLIM6 antibody, ZASP antibody, LDB3 antibody, Z-band alternatively spliced PDZ-motif protein antibody, protein cypher antibody, PDZ and LIM domain 6 antibody, LIM domain-binding protein 3 antibody, LIM domain binding 3 antibody
Cellular Localization: Cytoplasm , perinuclear region , Cell projection , pseudopodium , cytoskeleton , myofibril , sarcomere , Z-disk
CAS NO: 148-79-8
Product: Azimilide
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of human LDB3. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Storage Buffer: 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24130765?dopt=Abstract
