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Product Name: eIF2 alpha antibody [EIF2a]
Applications: WB
Predicted Target Size:
Positive Controls: Human Jurkat, CEM and HeLa cells, mouse 3T3L1 and rat PC-12 cells
Form Supplied: Liquid
Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Protein A purified
Full Name: eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
Background: The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010]
Synonyms: EIF2 Antibody , EIF-2 Antibody , EIF-2ALPHA Antibody , EIF-2A Antibody , EIF2S1 Antibody , EIF2A Antibody
Cellular Localization:
CAS NO: 202917-17-7
Product: Daclatasvir
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: Recombinant full length protein (Human).
Antigen Species: Human
Species Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Storage Buffer: Preservative: 0.1% Sodium Azide; Constituents: PBS. pH 7.4
Storage Instruction: Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody recognizes the alpha subunit of eukaryotic translation initiation factor 2 (eIF-2A).
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22442699?dopt=Abstract

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