Product Name: Elongin B antibody
Applications: ICC/IF, IHC-P, WB
Predicted Target Size: 13 KDa (note)
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification: Affinity purification
Full Name: transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
Background: This gene encodes the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. Pseudogenes have been identified on chromosomes 11 and 13. [provided by RefSeq, Aug 2008]
Synonyms: TCEB2 Antibody , ELOB Antibody , SIII Antibody , transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B) Antibody
Cellular Localization:
CAS NO: 154229-18-2
Product: Vinpocetine
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein of human TCEB2
Antigen Species: Human
Species Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Instruction: Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/26198001?dopt=Abstract
