Product Name: ENaC Alpha antibody [N3C2], Internal
Applications: IHC-P, WB
Predicted Target Size: 76 kDa (note) (3)
Positive Controls: 293T
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: sodium channel, nonvoltage-gated 1 alpha
Background: Nonvoltage-gated, amiloride-sensitive, sodium channels control fluid and electrolyte transport across epithelia in many organs. These channels are heteromeric complexes consisting of 3 subunits: alpha, beta, and gamma. This gene encodes the alpha subunit, and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1), a rare salt wasting disease resulting from target organ unresponsiveness to mineralocorticoids. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]
Synonyms: BESC2 antibody, ENaCa antibody, ENaCalpha antibody, FLJ21883 antibody, SCNEA antibody, SCNN1 antibody, SCNN1A antibody, alpha ENaC-2 antibody, amiloride-sensitive epithelial sodium channel alpha subunit antibody, amiloride-sensitive sodium channel subunit alpha 2 antibody, epithelial Na(+) channel subunit alpha antibody, amiloride-sensitive sodium channel subunit alpha antibody, nasal epithelial sodium channel alpha subunit antibody, alpha-NaCH antibody, nonvoltage-gated sodium channel 1 subunit alpha antibody, alpha-ENaC antibody, “sodium channel, nonvoltage-gated 1 alpha antibody”
Cellular Localization: Apical cell membrane; Multi-pass membrane protein
CAS NO: 1001350-96-4
Product: PF 03716556
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of human ENaC Alpha. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: 1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22581778?dopt=Abstract
