Product Name: Eps15 (phospho Tyr849) antibody
Applications: WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Full Name: epidermal growth factor receptor pathway substrate 15
Background: This gene encodes a protein that is part of the EGFR pathway. The protein is present at clatherin-coated pits and is involved in receptor-mediated endocytosis of EGF. Notably, this gene is rearranged with the HRX/ALL/MLL gene in acute myelogeneous leukemias. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, May 2009]
Synonyms: epidermal growth factor receptor pathway substrate 15 Antibody , EPS15 Antibody , AF1P Antibody , MLLT5 Antibody , AF-1P Antibody
Cellular Localization:
CAS NO: 779353-01-4
Product: PD173074
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Peptide sequence around phosphorylation site of tyrosine 849 (S-A-Y(p)-P-S) derived from Human Ephrin EPS15.
Antigen Species: Human
Species Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Storage Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Instruction: Store at -20˚C/1 year
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: The antibody detects endogenous levels of EPS15 only when phosphorylated at tyrosine 849.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/26268247?dopt=Abstract
