Product Name: eIF3 p110 antibody [C2C3], C-term
Applications: WB
Predicted Target Size: 105 kDa (note) (5)
Positive Controls: 293T , A431 , Jurkat , Raji
Form Supplied: Liquid
Concentration: 0.9 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: eukaryotic translation initiation factor 3, subunit C
Background: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
Synonyms: EIF3CL antibody, EIF3S8 antibody, FLJ53378 antibody, FLJ54400 antibody, FLJ54404 antibody, FLJ55450 antibody, FLJ55750 antibody, FLJ78287 antibody, MGC189737 antibody, MGC189744 antibody, eIF3-p110 antibody, EIF3C antibody, eukaryotic translation initiation factor 3 subunit 8 antibody, eukaryotic translation initiation factor 3 subunit C antibody, cell migration-inducing protein 17 antibody, “eukaryotic translation initiation factor 3, subunit 8 (110kD) antibody”, eIF3 p110 antibody, “eukaryotic translation initiation factor 3, subunit 8, 110kDa antibody”, “eukaryotic translation initiation factor 3, subunit C antibody”
Cellular Localization: Cytoplasm
CAS NO: 910232-84-7
Product: VX-222
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human eIF3 p110. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21655189?dopt=Abstract
