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Product Name: DYNLL1 antibody [9S2]
Applications: WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification: The IgG fraction of culture supernatant was purified by Protein G affinity chromatography
Full Name: dynein, light chain, LC8-type 1
Background: Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]
Synonyms: DNCL1 Antibody , dynein, light chain, LC8-type 1 Antibody , LC8a Antibody , hdlc1 Antibody , DLC1 Antibody , LC8 Antibody , DNCLC1 Antibody , DYNLL1 Antibody , DLC8 Antibody
Cellular Localization:
CAS NO: 1159824-67-5
Product: Vicriviroc (maleate)
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: The immunogen sequence is the full length 89AA of human DYNLL1.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: PBS
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody was selected for its ability to specifically detect human DYNLL1.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/26446219?dopt=Abstract

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