Product Name: Dystrophin antibody [MANDRA1]
Applications: ELISA, ICC/IF, IHC-Fr, WB
Predicted Target Size:
Positive Controls: human muscle
Form Supplied: Liquid
Concentration:
Purification: Unpurified
Full Name: dystrophin
Background: The C-terminal domain of the human dystrophin molecule (a. A. residues 3558-3684) is present in normal muscle tissue. It is also present in nearly all Becker muscular dystrophies, but is absent in cases of Duchenne muscular dystrophies and in the dystrophic mouse (mdx) (ref 1-3).
Synonyms: Dystrophin, DXS269, DXS272, 1756, DXS268, DXS239, DXS270, DXS142, 300376, DXS206, P11532, DXS230, DMD, DXS164, BMD
Cellular Localization:
CAS NO: 158681-13-1
Product: GW791343 (dihydrochloride)
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: fusion protein containing the C-terminal 485 amino acids (3200-3684) of human dystrophine.
Antigen Species: Human
Species Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Storage Buffer: Ascites, 15 mM sodium azide
Storage Instruction: Keep as concentrated solution. For short-term storage, store at 4° C (up to 10 days). For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: The C-terminal domain of the human dystrophin molecule (amino acids residues 3558-3684) is present in normal muscle tissue. It is also present in nearly all Becker muscular dystrophies, but is absent in cases of Duchenne muscular dystrophies and in the dystrophic mouse (mdx).
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25979247?dopt=Abstract
