Product Name: EAAT2 antibody, Internal
Applications: IHC-P
Predicted Target Size: 62 KDa (note)
Positive Controls:
Form Supplied: Liquid
Concentration: 0.5-1 mg/ml
Purification: Affinity Purified
Full Name: solute carrier family 1 member 2
Background: This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Sep 2010]
Synonyms: GLT1 Antibody , EAAT2 Antibody , SLC1A2 Antibody
Cellular Localization:
CAS NO: 1009119-64-5
Product: Alvespimycin
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: A synthetic peptide corresponding to an Internal region of Human EAAT2.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Storage Instruction: Keep as concentrated solution. For short-term storage, store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24344294?dopt=Abstract
