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Product Name: Filamin B antibody [GT1282]
Applications: IHC-P, WB
Predicted Target Size: 278 kDa (note) (4)
Positive Controls: 293T , A431 , HeLa , HepG2
Form Supplied: Liquid
Concentration: 1.83 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Affinity purified by Protein G.
Full Name: filamin B, beta
Background: This gene encodes a member of the filamin family. The encoded protein interacts with glycoprotein Ib alpha as part of the process to repair vascular injuries. The platelet glycoprotein Ib complex includes glycoprotein Ib alpha, and it binds the actin cytoskeleton. Mutations in this gene have been found in several conditions: atelosteogenesis type 1 and type 3; boomerang dysplasia; autosomal dominant Larsen syndrome; and spondylocarpotarsal synostosis syndrome. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq]
Synonyms: AOI Antibody , filamin B, beta Antibody , FLN1L Antibody , LRS1 Antibody , FLNB Antibody , TABP Antibody , SCT Antibody , ABP-280 Antibody , FLN-B Antibody , ABP-278 Antibody , FH1 Antibody , TAP Antibody
Cellular Localization: Isoform 1: Cytoplasm , cell cortex , Cytoplasm , cytoskeleton , myofibril , sarcomere , Z-disk , Isoform 2: Cytoplasm , Isoform 3: Cytoplasm , Isoform 6: Cytoplasm
CAS NO: 27013-91-8
AdipoRon
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human Filamin B. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human, Rat
Conjugation: Unconjugated
Storage Buffer: PBS
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24919622?dopt=Abstract

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