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Product Name: IL12 antibody [C8.6] (Biotin)
Applications: Blocking, ELISA, WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration: 0.50 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Protein A
Full Name: interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
Background: This gene encodes a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity. [provided by RefSeq, Jul 2008]
Synonyms: IL-12A Antibody , CLMF Antibody , P35 Antibody , IL12A Antibody , interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) Antibody , NKSF1 Antibody , NFSK Antibody
Cellular Localization:
CAS NO: 130-16-5
Product: M2I-1
Host: Rat
Clonality: Monoclonal
Isotype: IgG1
Immunogen: Recombinant human IL-12 (p70)
Antigen Species: Human
Species Reactivity: Human
Conjugation: Biotin
Storage Buffer: PBS containing 4 % BSA
Storage Instruction: -20°C
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20629633?dopt=Abstract

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